Diabetic nephropathy (DN)
is a leading cause of mortality and morbidity in patients with diabetes. It is
the single major cause of renal failure in many countries.
Diabetic Nephropathy |
This complication reflects
a complex pathophysiology, whereby various genetic and environmental factors
determine susceptibility and progression to end-stage renal disease. End-stage
renal disease (ESRD) due to diabetes has been estimated to be 30-47% of all
incident cases worldwide. Disparities in the incidence of ESRD from diabetes
among ethnic groups have existed for many years, but the magnitude has been
increasing. The World Health Organization (WHO) has estimated that there are
currently 346 million people affected by diabetes worldwide and anticipates
that diabetes-related deaths would double by 2030.
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